CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family Glutathione S-transferase 2

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P30112
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P30112
GST26_FASHE
Fasciola hepatica
Glutathione S-transferase class-mu 26 kDa isozyme 51

PDB Structure

PDB 2WRT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The 2.5 Angstrom Structure of a Mu Class Gst from Fasciola Hepatica
Line, K., Isupov, M.N., Lacourse, E.J., Brophy, P.M., Littlechild, J.A.
To be Published