CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase |
Enzyme Information
| 4.1.1.45 |
Aminocarboxymuconate-semialdehyde decarboxylase.
based on mapping to UniProt Q8TDX5
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate semialdehyde + CO(2).
-!- The product rearranges non-enzymically to picolinate.
|
UniProtKB Entries (1)
| Q8TDX5 |
ACMSD_HUMAN
Homo sapiens
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
|
PDB Structure
| PDB | 2WM1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal Structure of Human Alpha-Amino-Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase in Complex with 1,3-Dihydroxyacetonephosphate Suggests a Regulatory Link between Nad Synthesis and Glycolysis
FEBS J.
|