CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.120
Functional Family Complement C3

Enzyme Information

UniProtKB Entries (2)

Q6GFB4
SCIN_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcal complement inhibitor
P00751
CFAB_HUMAN
Homo sapiens
Complement factor B

PDB Structure

PDB 2WIN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Rooijakkers, S.H., Wu, J., Ruyken, M., van Domselaar, R., Planken, K.L., Tzekou, A., Ricklin, D., Lambris, J.D., Janssen, B.J., van Strijp, J.A., Gros, P.
Nat. Immunol.