CATH Classification

Domain Context

CATH Clusters

Superfamily HAD superfamily/HAD-like
Functional Family Beta-phosphoglucomutase

Enzyme Information

5.4.2.6
Beta-phosphoglucomutase.
based on mapping to UniProt P71447
Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.
-!- The enzyme is able to autophosphorylate itself with its substrate beta-D-glucose 1-phosphate. -!- Although this is a slow reaction, only a single turnover is required for activation. -!- Once the phosphorylated enzyme is formed, it generates the reaction intermediate beta-D-glucose 1,6-bisphosphate, which can be used to phosphorylate the enzyme in subsequent cycles. -!- Cf. EC 5.4.2.2.

UniProtKB Entries (1)

P71447
PGMB_LACLA
Lactococcus lactis subsp. lactis Il1403
Beta-phosphoglucomutase

PDB Structure

PDB 2WF5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Baxter, N.J., Bowler, M.W., Alizadeh, T., Cliff, M.J., Hounslow, A.M., Wu, B., Berkowitz, D.B., Williams, N.H., Blackburn, G.M., Waltho, J.P.
Proc. Natl. Acad. Sci. U.S.A.