CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Exo-beta-D-glucosaminidase

Enzyme Information

3.2.1.165
Exo-1,4-beta-D-glucosaminidase.
based on mapping to UniProt Q56F26
Hydrolysis of chitosan or chitosan oligosaccharides to remove successive D-glucosamine residues from the non-reducing termini.
-!- Chitosan is a partially or totally N-deacetylated chitin derivative that is found in the cell walls of some phytopathogenic fungi and comprises D-glucosamine residues with a variable content of GlcNAc residues. -!- Acts specifically on chitooligosaccharides and chitosan, having maximal activity on chitotetraose, chitopentaose and their corresponding alcohols. -!- Can degrade GlcN-GlcNAc but not GlcNAc-GlcNAc.

UniProtKB Entries (1)

Q56F26
EBDG_AMYOR
Amycolatopsis orientalis
Exo-beta-D-glucosaminidase

PDB Structure

PDB 2VZV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structural Basis of Substrate Recognition in an Exo-Beta-D-Glucosaminidase Involved in Chitosan Hydrolysis.
Lammerts Van Bueren, A., Ghinet, M.G., Gregg, K., Fleury, A., Brzezinski, R., Boraston, A.B.
J.Mol.Biol.