CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P56689
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P56689
DPOL_THEGO
Thermococcus gorgonarius
DNA polymerase

PDB Structure

PDB 2VWK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography.
Firbank, S.J., Wardle, J., Heslop, P., Lewis, R.J., Connolly, B.A.
J.Mol.Biol.