CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
Functional Family

Enzyme Information

1.18.1.2
Ferredoxin--NADP(+) reductase.
based on mapping to UniProt Q9L6V3
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
-!- In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin. -!- Formerly EC 1.6.7.1 and EC 1.6.99.4.
1.19.1.1
Flavodoxin--NADP(+) reductase.
based on mapping to UniProt Q9L6V3
Reduced flavodoxin + NADP(+) = oxidized flavodoxin + NADPH.
-!- This activity occurs in some prokaryotes and algae that possess flavodoxin, and provides low-potential electrons for a variety of reactions such as nitrogen fixation, sulfur assimilation and amino acid biosynthesis. -!- In photosynthetic organisms it is involved in the photosynthetic electron transport chain. -!- The enzyme also catalyzes EC 1.18.1.2.

UniProtKB Entries (1)

Q9L6V3
FENR_RHOCA
Rhodobacter capsulatus
Flavodoxin/ferredoxin--NADP reductase

PDB Structure

PDB 2VNI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Coenzyme Binding and Hydride Transfer in Rhodobacter Capsulatus Ferredoxin/Flavodoxin Nadp(H) Oxidoreductase.
Bortolotti, A., Perez-Dorado, I., Goni, G., Medina, M., Hermoso, J.A., Carrillo, N., Cortez, N.
Biochim.Biophys.Acta