CATH Classification

Domain Context

CATH Clusters

Superfamily Zinc/RING finger domain, C3HC4 (zinc finger)
Functional Family MDM4 isoform 3

Enzyme Information

UniProtKB Entries (1)

Q00987
MDM2_HUMAN
Homo sapiens
E3 ubiquitin-protein ligase Mdm2

PDB Structure

PDB 2VJE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
Linke, K., Mace, P.D., Smith, C.A., Vaux, D.L., Silke, J., Day, C.L.
Cell Death Differ.