CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Alanine dehydrogenase

Enzyme Information

1.4.1.1
Alanine dehydrogenase.
based on mapping to UniProt P9WQB1
L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH.

UniProtKB Entries (1)

P9WQB1
DHA_MYCTU
Mycobacterium tuberculosis H37Rv
Alanine dehydrogenase

PDB Structure

PDB 2VHX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding.
Agren, D., Stehr, M., Berthold, C.L., Kapoor, S., Oehlmann, W., Singh, M., Schneider, G.
J.Mol.Biol.