CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Aspartate-semialdehyde dehydrogenase

Enzyme Information

1.2.1.11
Aspartate-semialdehyde dehydrogenase.
based on mapping to UniProt P23247
L-aspartate 4-semialdehyde + phosphate + NADP(+) = L-4-aspartyl phosphate + NADPH.

UniProtKB Entries (1)

P23247
DHAS2_VIBCH
Vibrio cholerae O1 biovar El Tor str. N16961
Aspartate-semialdehyde dehydrogenase 2

PDB Structure

PDB 2R00
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Viola, R.E., Liu, X., Ohren, J.F., Faehnle, C.R.
Acta Crystallogr.,Sect.D