CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.200.40
Functional Family Diacylglycerol kinase

Enzyme Information

2.7.1.107
Diacylglycerol kinase (ATP).
based on mapping to UniProt Q6GFF9
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
-!- Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. -!- Activity is stimulated by certain phospholipids. -!- In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. -!- cf. EC 2.7.1.174.

UniProtKB Entries (1)

Q6GFF9
DAGK_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Diacylglycerol kinase

PDB Structure

PDB 2QVL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Analysis of the Staphylococcus aureus DgkB Structure Reveals a Common Catalytic Mechanism for the Soluble Diacylglycerol Kinases.
Miller, D.J., Jerga, A., Rock, C.O., White, S.W.
Structure