CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt P23381
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

P23381
SYWC_HUMAN
Homo sapiens
Tryptophan--tRNA ligase, cytoplasmic

PDB Structure

PDB 2QUI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
Shen, N., Zhou, M., Yang, B., Yu, Y., Dong, X., Ding, J.
Nucleic Acids Res.