CATH Domain 2q6fA03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1840	main proteinase (3clpro) structure, domain 3
	1.10.1840.10	main proteinase (3clpro) structure, domain 3

Domain Context

CATH Clusters

Superfamily	main proteinase (3clpro) structure, domain 3
Functional Family

Enzyme Information

3.4.22.-

Cysteine endopeptidases.

based on mapping to UniProt P0C6V5

UniProtKB Entries (1)

R1A_IBVM

Avian infectious bronchitis virus (strain M41)

Replicase polyprotein 1a

PDB Structure

PDB	2Q6F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. Xue, X., Yu, H., Yang, H., Xue, F., Wu, Z., Shen, W., Li, J., Zhou, Z., Ding, Y., Zhao, Q., Zhang, X.C., Liao, M., Bartlam, M., Rao, Z. J.Virol.