CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.900 | Dbl Homology Domain; Chain A |
|
1.20.900.10 | Dbl homology (DH) domain |
Domain Context
CATH Clusters
| Superfamily | Dbl homology (DH) domain |
| Functional Family | Rho guanine nucleotide exchange factor 9 |
Enzyme Information
UniProtKB Entries (1)
| Q9NR80 |
ARHG4_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 4
|
PDB Structure
| PDB | 2PZ1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Nat.Struct.Mol.Biol.
|