1 keywords

CATH Domain 2p7uA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.70 Cathepsin B; Chain A
Homologous Superfamily 3.90.70.10 Cysteine proteinases

Domain Context

CATH Clusters

Superfamily Cysteine proteinases
Functional Family Cruzipain

Enzyme Information

UniProtKB Entries (1)

Q95PM0
Q95PM0_TRYBR
Trypanosoma brucei rhodesiense
Cysteine protease

PDB Structure

PDB 2P7U
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
Kerr, I.D., Lee, J.H., Farady, C.J., Marion, R., Rickert, M., Sajid, M., Pandey, K.C., Caffrey, C.R., Legac, J., Hansell, E., McKerrow, J.H., Craik, C.S., Rosenthal, P.J., Brinen, L.S.
J.Biol.Chem.