CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.140 | Epsilon-Thrombin; Chain L |
|
4.10.140.10 | Thrombin light chain domain |
Domain Context
CATH Clusters
| Superfamily | Thrombin light chain domain |
| Functional Family |
Enzyme Information
| 3.4.21.5 |
Thrombin.
based on mapping to UniProt P00735
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.
-!- More selective than trypsin and plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.13.
|
UniProtKB Entries (2)
| P00735 |
THRB_BOVIN
Bos taurus
Prothrombin
|
| Q8WPI2 |
BOOH2_RHIMP
Rhipicephalus microplus
Boophilin-H2
|
PDB Structure
| PDB | 2ODY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick.
Plos One
|