CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.80
Isopropanol dehydrogenase (NADP(+)).
based on mapping to UniProt P14941
Propan-2-ol + NADP(+) = acetone + NADPH.
-!- Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.

UniProtKB Entries (1)

P14941
ADH_THEBR
Thermoanaerobacter brockii
NADP-dependent isopropanol dehydrogenase

PDB Structure

PDB 2NVB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution
Goihberg, E., Dym, O., Tel-Or, S., Shimon, L., Frolow, F., Peretz, M., Burstein, Y.
Proteins