CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family carboxypeptidase N catalytic chain

Enzyme Information

3.4.17.3
Lysine carboxypeptidase.
based on mapping to UniProt P15169
Release of a C-terminal basic amino acid, preferentially lysine.
-!- Inactivates bradykinin and anaphylatoxins in blood plasma. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.12.7.

UniProtKB Entries (1)

P15169
CBPN_HUMAN
Homo sapiens
Carboxypeptidase N catalytic chain

PDB Structure

PDB 2NSM
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain
Keil, C., Maskos, K., Than, M., Hoopes, J.T., Huber, R., Tan, F., Deddish, P.A., Erdoes, E.G., Skidgel, R.A., Bode, W.
J.Mol.Biol.