CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | KRAS proto-oncogene, GTPase |
Enzyme Information
UniProtKB Entries (1)
| P02647 |
APOA1_HUMAN
Homo sapiens
Apolipoprotein A-I
|
PDB Structure
| PDB | 2MSD |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
Proc.Natl.Acad.Sci.USA
|