CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.465 | Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 |
|
3.30.465.10 |
Domain Context
CATH Clusters
| Superfamily | 3.30.465.10 |
| Functional Family | UDP-N-acetylenolpyruvoylglucosamine reductase |
Enzyme Information
| 1.3.1.98 |
UDP-N-acetylmuramate dehydrogenase.
based on mapping to UniProt P08373
UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.
|
UniProtKB Entries (1)
| P08373 |
MURB_ECOLI
Escherichia coli K-12
UDP-N-acetylenolpyruvoylglucosamine reductase
|
PDB Structure
| PDB | 2MBR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution.
Biochemistry
|