CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.246 | Serum Albumin; Chain A, Domain 1 |
|
1.10.246.20 | Coactivator CBP, KIX domain |
Domain Context
CATH Clusters
| Superfamily | Coactivator CBP, KIX domain |
| Functional Family | E1A binding protein p300 |
Enzyme Information
| 2.3.1.48 |
Histone acetyltransferase.
based on mapping to UniProt Q92793
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
|
UniProtKB Entries (1)
| Q92793 |
CBP_HUMAN
Homo sapiens
CREB-binding protein
|
PDB Structure
| PDB | 2KWF |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
To be Published
|