CATH Classification
Domain Context
CATH Clusters
| Superfamily | Calcium-transporting ATPase, cytoplasmic transduction domain A |
| Functional Family | Copper-transporting ATPase 1, putative |
Enzyme Information
| 7.2.2.8 |
P-type Cu(+) transporter.
based on mapping to UniProt Q04656
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.
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UniProtKB Entries (1)
| Q04656 |
ATP7A_HUMAN
Homo sapiens
Copper-transporting ATPase 1
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PDB Structure
| PDB | 2KIJ |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins
Biochemistry
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