CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.171
16S rRNA (guanine(966)-N(2))-methyltransferase.
based on mapping to UniProt P44869
S-adenosyl-L-methionine + guanine(966) in 16S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(966) in 16S rRNA.
-!- The enzyme efficiently methylates guanine(966) of the assembled 30S subunits in vitro. -!- Protein-free 16S rRNA is not a substrate for RsmD. -!- The enzyme specifically methylates guanine(966) at N(2) in 16S rRNA. -!- Formerly EC 2.1.1.52.

UniProtKB Entries (1)

P44869
RSMD_HAEIN
Haemophilus influenzae Rd KW20
Ribosomal RNA small subunit methyltransferase D

PDB Structure

PDB 2IFT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the putative methylase HI0767 from Haemophilus influenzae.
Vorobiev, S.M., Su, M., Seetharaman, J., Shastry, R., Janjua, H., Ma, L.C., Xiao, R., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F.
To be Published