CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1330 | 60s Ribosomal Protein L30; Chain: A; |
|
3.30.1330.70 | Holliday junction resolvase RusA |
Domain Context
CATH Clusters
| Superfamily | Holliday junction resolvase RusA |
| Functional Family | Crossover junction endodeoxyribonuclease RusA |
Enzyme Information
| 3.1.22.4 |
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt P0AG74
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.
|
UniProtKB Entries (1)
| P0AG74 |
RUSA_ECOLI
Escherichia coli K-12
Crossover junction endodeoxyribonuclease RusA
|
PDB Structure
| PDB | 2H8E |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
RusA Holliday junction resolvase: DNA complex structure--insights into selectivity and specificity.
Nucleic Acids Res.
|