CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Dihydropyrimidinase like 3

Enzyme Information

3.5.2.2
Dihydropyrimidinase.
based on mapping to UniProt Q55DL0
5,6-dihydrouracil + H(2)O = 3-ureidopropanoate.
-!- Also acts on dihydrothymine and hydantoin.

UniProtKB Entries (1)

Q55DL0
DPYS_DICDI
Dictyostelium discoideum
Dihydropyrimidinase

PDB Structure

PDB 2FTW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
Lohkamp, B., Andersen, B., Piskur, J., Dobritzsch, D.
J.Biol.Chem.