CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family ATP-dependent RNA helicase DHX8

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q14562
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q14562
DHX8_HUMAN
Homo sapiens
ATP-dependent RNA helicase DHX8

PDB Structure

PDB 2EQS
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the S1 RNA binding domain of human ATP-dependent RNA helicase DHX8
Suzuki, S., Muto, Y., Inoue, M., Kigawa, T., Terada, T., Shirouzu, M., Yokoyama, S.
To be Published