CATH Classification

Domain Context

CATH Clusters

Superfamily Intein homing endonuclease, domain III
Functional Family

Enzyme Information

3.1.-.-
Acting on ester bonds.
based on mapping to UniProt P77933
2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P77933
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P77933
DPOL_THEKO
Thermococcus kodakarensis KOD1
DNA polymerase

PDB Structure

PDB 2CW8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1
Matsumura, H., Takahashi, H., Inoue, T., Yamamoto, T., Hashimoto, H., Nishioka, M., Fujiwara, S., Takagi, M., Imanaka, T., Kai, Y.
Proteins