CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Serine--pyruvate aminotransferase, mitochondrial

Enzyme Information

2.6.1.44
Alanine--glyoxylate transaminase.
based on mapping to UniProt P43567
L-alanine + glyoxylate = pyruvate + glycine.
-!- With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. -!- A second component also catalyzes the reaction of EC 2.6.1.51.

UniProtKB Entries (1)

P43567
AGX1_YEAST
Saccharomyces cerevisiae S288C
Alanine--glyoxylate aminotransferase 1

PDB Structure

PDB 2BKW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure and Confirmation of the Alanine:Glyoxylate Aminotransferase Activity of the Yfl030W Yeast Protein
Meyer, P., Liger, D., Leulliot, N., Quevillon-Cheruel, S., Zhou, C.Z., Borel, F., Ferrer, J.L., Poupon, A., Janin, J., Van Tilbeurgh, H.
Biochimie