CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin

PDB Structure

PDB 2AH4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Radisky, E.S., Lee, J.M., Lu, C.J., Koshland Jr., D.E.
Proc.Natl.Acad.Sci.USA