CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10230 | Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase |
Domain Context
CATH Clusters
| Superfamily | Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase |
| Functional Family |
Enzyme Information
| 5.4.99.60 |
Cobalt-precorrin-8 methylmutase.
based on mapping to UniProt Q8EXP7
Cobalt-precorrin-8 = cobyrinate.
-!- The enzyme catalyzes the the conversion of cobalt-precorrin-8 to cobyrinate by methyl rearrangement, a step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis. -!- The equivalent enzyme in the aerobic pathway is EC 5.4.99.61.
|
UniProtKB Entries (1)
| Q8EXP7 |
CBIC_LEPIN
Leptospira interrogans serovar Lai str. 56601
Cobalt-precorrin-8 methylmutase
|
PDB Structure
| PDB | 2AFV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis
J.Struct.Biol.
|