CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Aspartate aminotransferase

Enzyme Information

2.6.1.1
Aspartate transaminase.
based on mapping to UniProt P00509
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

UniProtKB Entries (1)

P00509
AAT_ECOLI
Escherichia coli K-12
Aspartate aminotransferase

PDB Structure

PDB 2AAT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli.
Smith, D.L., Almo, S.C., Toney, M.D., Ringe, D.
Biochemistry