CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Guanylate kinase

Enzyme Information

2.7.4.8
Guanylate kinase.
based on mapping to UniProt P9WKE9
ATP + GMP = ADP + GDP.
-!- dGMP can also act as acceptor. -!- dATP can act as donor.

UniProtKB Entries (1)

P9WKE9
KGUA_MYCTU
Mycobacterium tuberculosis H37Rv
Guanylate kinase

PDB Structure

PDB 1ZNY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase
Hible, G., Christova, P., Renault, L., Seclaman, E., Thompson, A., Girard, E., Munier-Lehmann, H., Cherfils, J.
Proteins