CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family hematopoietic prostaglandin D synthase

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt Q09596
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

Q09596
GST5_CAEEL
Caenorhabditis elegans
Probable glutathione S-transferase 5

PDB Structure

PDB 1ZL9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a major nematode C.elegans specific GST (CE01613)
Kriksunov, I.A., Liu, Q., Schuller, D.J., Campbell, A.M., Barrett, J., Brophy, P.M., Hao, Q.
To be Published