CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2300
Functional Family Low molecular weight phosphotyrosine protein

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P11064
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
3.1.3.2
Acid phosphatase.
based on mapping to UniProt P11064
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Wide specificity. -!- Also catalyzes transphosphorylations.

UniProtKB Entries (1)

P11064
PPAC_BOVIN
Bos taurus
Low molecular weight phosphotyrosine protein phosphatase

PDB Structure

PDB 1Z12
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Bovine Low Molecular Weight Phosphotyrosyl Phosphatase Complexed with the Transition State Analog Vanadate
Zhang, M., Zhou, M., Van Etten, R.L., Stauffacher, C.V.
Biochemistry