CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Ephrin type-A receptor 5

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P29322
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P29322
EPHA8_HUMAN
Homo sapiens
Ephrin type-A receptor 8

PDB Structure

PDB 1X5L
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the second fn3 domain of Eph receptor A8 protein
Qin, X.R., Nagashima, T., Hayashi, F., Yokoyama, S.
To be published