CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 1
Functional Family N-succinylglutamate 5-semialdehyde dehydrogenase

Enzyme Information

1.2.1.90
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)).
based on mapping to UniProt O57693
D-glyceraldehyde 3-phosphate + NAD(P)(+) + H(2)O = 3-phospho-D-glycerate + NAD(P)H.
-!- The enzyme is part of the modified Embden-Meyerhof-Parnas pathway of the archaeon Thermoproteus tenax (cf. EC 1.2.1.9).

UniProtKB Entries (1)

O57693
GAPN_THETE
Thermoproteus tenax
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 1UXR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax
Lorentzen, E., Hensel, R., Knura, T., Ahmed, H., Pohl, E.
J.Mol.Biol.