CATH Classification

Domain Context

CATH Clusters

Superfamily Homocysteine-binding-like domain
Functional Family Betaine--homocysteine S-methyltransferase 1

Enzyme Information

2.1.1.5
Betaine--homocysteine S-methyltransferase.
based on mapping to UniProt O09171
Trimethylammonioacetate + L-homocysteine = dimethylglycine + L-methionine.

UniProtKB Entries (1)

O09171
BHMT1_RAT
Rattus norvegicus
Betaine--homocysteine S-methyltransferase 1

PDB Structure

PDB 1UMY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding.
Gonzalez, B., Pajares, M.A., Martinez-Ripoll, M., Blundell, T.L., Sanz-Aparicio, J.
J. Mol. Biol.