CATH Classification

Domain Context

CATH Clusters

Superfamily GHMP Kinase, N-terminal domain
Functional Family Ribonuclease PH

Enzyme Information

2.7.7.56
tRNA nucleotidyltransferase.
based on mapping to UniProt O67069
tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.
-!- Brings about the final exonucleolytic trimming of the 3'-terminus of tRNA precursors in Escherichia coli by a phosphorolysis, producing a mature 3'-terminus in tRNA and nucleoside diphosphate. -!- Not identical with EC 2.7.7.8.

UniProtKB Entries (1)

O67069
RNPH_AQUAE
Aquifex aeolicus VF5
Ribonuclease PH

PDB Structure

PDB 1UDN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of the tRNA Processing Enzyme RNase PH from Aquifex aeolicus
Ishii, R., Nureki, O., Yokoyama, S.
J.Biol.Chem.