CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P09792
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P09792
GST28_SCHMA
Schistosoma mansoni
Glutathione S-transferase class-mu 28 kDa isozyme

PDB Structure

PDB 1U3I
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Schistosoma mansoni glutathione S-transferase
Chomilier, J., Vaney, M.C., Labesse, G., Trottein, F., Capron, A., Mormon, J.-P.
To be Published