CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Triosephosphate isomerase

Enzyme Information

4.2.3.3
Methylglyoxal synthase.
based on mapping to UniProt P00940
Glycerone phosphate = methylglyoxal + phosphate.
-!- Does not act on D-glyceraldehyde 3-phosphate. -!- Formerly EC 4.2.99.11.
5.3.1.1
Triose-phosphate isomerase.
based on mapping to UniProt P00940
D-glyceraldehyde 3-phosphate = glycerone phosphate.

UniProtKB Entries (1)

P00940
TPIS_CHICK
Gallus gallus
Triosephosphate isomerase

PDB Structure

PDB 1TPV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Komives, E.A., Lougheed, J.C., Zhang, Z., Sugio, S., Narayana, N., Xuong, N.H., Petsko, G.A., Ringe, D.
Biochemistry