CATH Classification

Domain Context

CATH Clusters

Superfamily 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
Functional Family 4-hydroxyphenylpyruvate dioxygenase

Enzyme Information

1.13.11.27
4-hydroxyphenylpyruvate dioxygenase.
based on mapping to UniProt P93836
4-hydroxyphenylpyruvate + O(2) = homogentisate + CO(2).
-!- Formerly EC 1.14.2.2 and EC 1.99.1.14.

UniProtKB Entries (1)

P93836
HPPD_ARATH
Arabidopsis thaliana
4-hydroxyphenylpyruvate dioxygenase

PDB Structure

PDB 1TG5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Yang, C., Pflugrath, J.W., Camper, D.L., Foster, M.L., Pernich, D.J., Walsh, T.A.
Biochemistry