CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family Alkyl hydroperoxide reductase, F subunit

Enzyme Information

1.8.1.9
Thioredoxin-disulfide reductase.
based on mapping to UniProt P0A9P4
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.

UniProtKB Entries (1)

P0A9P4
TRXB_ECOLI
Escherichia coli K-12
Thioredoxin reductase

PDB Structure

PDB 1TDF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
Waksman, G., Krishna, T.S.R., Williams Jr., C.H., Kuriyan, J.
J.Mol.Biol.