CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.90
Functional Family Thermonuclease

Enzyme Information

3.1.31.1
Micrococcal nuclease.
based on mapping to UniProt P00644
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.
-!- Hydrolyzes double- or single-stranded substrate. -!- Similar enzymes: Chlamydomonas nuclease, spleen phosphodiesterase, spleen endonuclease. -!- Formerly EC 3.1.4.7.

UniProtKB Entries (1)

P00644
NUC_STAAU
Staphylococcus aureus
Thermonuclease

PDB Structure

PDB 1SNO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Coupling between trans/cis proline isomerization and protein stability in staphylococcal nuclease.
Truckses, D.M., Somoza, J.R., Prehoda, K.E., Miller, S.C., Markley, J.L.
Protein Sci.