CATH Classification

CATH Clusters

Superfamily Golgi alpha-mannosidase II
Functional Family Pot. pancreatic alpha-amylase isozyme

Enzyme Information

3.2.1.1
Alpha-amylase.
based on mapping to UniProt P04745
Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.
-!- Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration. -!- The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed.

UniProtKB Entries (1)

P04745
AMY1_HUMAN
Homo sapiens
Alpha-amylase 1

PDB Structure

PDB 1SMD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human salivary alpha-amylase at 1.6 A resolution: implications for its role in the oral cavity.
Ramasubbu, N., Paloth, V., Luo, Y., Brayer, G.D., Levine, M.J.
Acta Crystallogr.,Sect.D