CATH Classification

Domain Context

CATH Clusters

Superfamily 2.70.40.10
Functional Family Deoxyuridine 5'-triphosphate nucleotidohydrolase

Enzyme Information

3.6.1.23
dUTP diphosphatase.
based on mapping to UniProt P9WNS5
dUTP + H(2)O = dUMP + diphosphate.

UniProtKB Entries (1)

P9WNS5
DUT_MYCTU
Mycobacterium tuberculosis H37Rv
Deoxyuridine 5'-triphosphate nucleotidohydrolase

PDB Structure

PDB 1SM8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
Chan, S., Segelke, B., Lekin, T., Krupka, H., Cho, U.S., Kim, M.-Y., So, M., Kim, C.-Y., Naranjo, C.M., Rogers, Y.C., Park, M.S., Waldo, G.S., Pashkov, I., Cascio, D., Perry, J.L., Sawaya, M.R.
J.Mol.Biol.