CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Radixin isoform 1

Enzyme Information

UniProtKB Entries (1)

O14745
NHRF1_HUMAN
Homo sapiens
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

PDB Structure

PDB 1SGH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
Finnerty, C.M., Chambers, D., Ingraffea, J., Faber, H.R., Karplus, P.A., Bretscher, A.
J.Cell.Sci.