CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family 4-hydroxy-tetrahydrodipicolinate synthase

Enzyme Information

4.3.3.7
4-hydroxy-tetrahydrodipicolinate synthase.
based on mapping to UniProt P0A6L2
Pyruvate + L-aspartate-4-semialdehyde = (4S)-4-hydroxy-2,3,4,5- tetrahydro-(2S)-dipicolinate + H(2)O.
-!- Formerly EC 4.2.1.52.

UniProtKB Entries (1)

P0A6L2
DAPA_ECOLI
Escherichia coli K-12
4-hydroxy-tetrahydrodipicolinate synthase

PDB Structure

PDB 1S5V
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
Dobson, R.C.J., Valegard, K., Gerrard, J.A.
J.MOL.BIOL.