CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.590.20
Functional Family

Enzyme Information

6.3.2.2
Glutamate--cysteine ligase.
based on mapping to UniProt P77213
ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L- cysteine.
-!- Can use L-aminohexanoate in place of glutamate.

UniProtKB Entries (1)

P77213
GCS2_ECOLI
Escherichia coli K-12
Putative glutamate--cysteine ligase 2

PDB Structure

PDB 1R8G
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
YbdK is a carboxylate-amine ligase with a gamma-glutamyl:Cysteine ligase activity: crystal structure and enzymatic assays
Lehmann, C., Doseeva, V., Pullalarevu, S., Krajewski, W., Howard, A., Herzberg, O.
PROTEINS: STRUCT.,FUNCT.,GENET.