CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.40.20
Functional Family Transitional endoplasmic reticulum ATPase

Enzyme Information

3.6.4.6
Vesicle-fusing ATPase.
based on mapping to UniProt Q01853
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.

UniProtKB Entries (1)

Q01853
TERA_MOUSE
Mus musculus
Transitional endoplasmic reticulum ATPase

PDB Structure

PDB 1R7R
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of murine p97/VCP at 3.6A
Huyton, T., Pye, V.E., Briggs, L.C., Flynn, T.C., Beuron, F., Kondo, H., Ma, J., Zhang, X., Freemont, P.S.
J.Struct.Biol.