CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.30 | SH3 type barrels. |
|
2.30.30.40 | SH3 Domains |
Domain Context
CATH Clusters
| Superfamily | SH3 Domains |
| Functional Family |
Enzyme Information
| 3.4.24.75 |
Lysostaphin.
based on mapping to UniProt O05156
Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans.
-!- Lyses cells of Staphylococcus aureus in particular, by its action on the cross-bridge of the cell wall. -!- Belongs to peptidase family M23.
|
UniProtKB Entries (1)
| O05156 |
ALE1_STACP
Staphylococcus capitis
Glycyl-glycine endopeptidase ALE-1
|
PDB Structure
| PDB | 1R77 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Cell Wall-targeting Domain of Glycylglycine Endopeptidase Distinguishes among Peptidoglycan Cross-bridges.
J.Biol.Chem.
|